In some cases, these drugs have been used as replacement therapy or as sole anticonvulsant agents. Regardless of the cause of the seizures, stopping further seizures is the most important aspect of management to remember. You must also note that clonazepam can interact poorly with certain other medications. The dose range for clonazepam has been reported as 0. To ensure the safety of your pet, you should seek the advice of a veterinarian before administering the drug to your dog, and notify them of all known diseases your dog suffers with, as well as any other medicine your dog is taking. However, there are inherent problems with benzodiazepines such as their physically addictive nature, which means that care must be taken when using this medication.
Relax: Clonazepam for dogs with seizures
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In general, use 1 ml IV for small dogs 5 - 10 kg , 2 ml IV for medium dogs 10 - 20 kg and 3 ml or more IV for large dogs greater than 20 kg. For cats use 0. If you cannot get IV access give double the IV dose rectally. Use a red rubber feeding tube inserted about 4 - 6 inches in the rectum and given as a bolus. If after giving a dose of diazepam the seizure does not stop within 2 - 3 minutes IV or 5 min rectal then give another dose. It is not that uncommon to have to give 2 - 4 doses of valium before the seizure stops.
It sounds like a lot but it is very safe. If an animal has compromised liver function or you are suspicious of liver disease shunt or cirrhosis etc Once the seizure is stopped you can give a loading dose of phenobarbital or potassium bromide. If you are going to refer the patient immediately, it might be better to wait on the loading dose so a more accurate exam can be performed. If the patient continues to have seizures after the initial doses of valium, they should be placed on a valium constant rate infusion.
Use the amount of valium that it took to stop the seizure and give it over one hour as a CRI. Dilute the phenobarbital in 1 part saline to one part phenobarbital and give it IV slowly. There have been anecdotal reports of animals having an anaphylactic reaction to components of the injectable form of phenobarbital. You can also give the loading dose orally, if you are certain that the patient is alert enough to take oral medications. While there are numerous causes of convulsions, treatments that control epileptic seizures are relatively limited.
Clonazepam is an infrequently used anticonvulsant. Clonazepam belongs to a class of drugs known as benzodiazepines. Related drugs include midazolam, diazepam, clorazepate and alprazolam. Clonazepam and these other related drugs exert their anticonvulsant effects by attaching to benzodiazepine receptors in the brain. Clonazepam is a prescription drug and can only be obtained from a veterinarian or by prescription from a veterinarian.
It is also a controlled substance. Clonazepam is not approved for use in animals by the Food and Drug Administration FDA but may be legally prescribed by veterinarians as an extra-label drug. None Uses of Clonazepam for Dogs and Cats Clonazepam is used to manage various types of seizures in human medicine and may be effective for this purpose in domestic animals, too.
A further veterinary application is for the treatment of anxiety and panic-type disorders in dogs and cats. Specific uses include treatment of thunderstorm phobia and other phobias, separation anxiety, and other situational fears, such as car travel or veterinary office visits. Like other benzodiazepines, clonazepam has muscle relaxant properties and may be used for this purpose. It is also used as an appetite stimulant and may alleviate the short-term effects of stress on irritable bowel syndrome.
In cats, clonazepam may be useful for treatment of feline hyperesthesia syndrome. Precautions and Side Effects While generally safe and effective when prescribed by a veterinarian, clonazepam may cause side effects in some animals. Clonazepam should not be used in animals with known hypersensitivity or allergy to the drug. It should also be avoided in patients with significant liver disease or glaucoma. Clonazepam should probably not be used in pregnant animals because it may increase the risk of birth defects.
In some animals, clonazepam may cause paradoxical reactions , including hyperactivity and aggression. Increased salivation may occur in some patients and may be problematic, particularly in dog breeds already prone to hypersalivation. Long-term treatment with clonazepam may lead to physical dependence and thus undesirable behavioral changes if the drug is discontinued abruptly.