Keep the medication in a place where others cannot get to it. What should I discuss with my healthcare provider before taking clonazepam Klonopin, Klonopin Wafer? If you have porphyria, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed. This drug should be used only if the potential benefit justifies the potential risk to the fetus. Therefore, discuss the risks and benefits of treatment with clonazepam with your doctor.
This oxygen substitution at R 2 is shared with other benzodiazepine drugs with the suffix -azepam. Benzodiazepines produce a variety of effects by binding to the benzodiazepine receptor site and magnifying the efficiency and effects of the neurotransmitter gamma aminobutyric acid GABA by acting on its receptors. The anticonvulsant properties of benzodiazepines may be, in part or entirely, due to binding to voltage-dependent sodium channels rather than benzodiazepine receptors.
The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects should be taken with a grain of salt and will rarely if ever occur all at once, but heavier doses will increase the chances and are more likely to induce a full range of effects.
Likewise, adverse effects become much more likely on higher doses and may include serious injury or death. There are currently no anecdotal reports which describe the effects of this compound within our experience index. Additional experience reports can be found here:. Clonazopam has a low toxicity relative to dose. It is strongly recommended that one use harm reduction practices when using this drug.
Tolerance will develop to the sedative-hypnotic effects within a couple of days of continuous use. After cessation, the tolerance returns to baseline in 7 - 14 days. However, in certain cases this may take significantly longer in a manner which is proportional to the duration and intensity of one's long-term usage. Withdrawal symptoms or rebound symptoms may occur after ceasing usage abruptly following a few weeks or longer of steady dosing, and may necessitate a gradual dose reduction.
For more information on tapering from benzodiazepines in a controlled manner, please see this guide. Benzodiazepine discontinuation is notoriously difficult; it is potentially life-threatening for individuals using regularly to discontinue use without tapering their dose over a period of weeks. There is an increased risk of hypertension , seizures , and death. Clonazopam presents cross-tolerance with all benzodiazepines , meaning that after its consumption all benzodiazepines will have a reduced effect.
Benzodiazepine overdose may occur when a benzodiazepine is taken in extremely heavy quantities or concurrently with other depressants. This is particularly dangerous with other GABAergic depressants such as barbiturates and alcohol since they work in a similar fashion, but bind to distinct allosteric sites on the GABA A receptor, thus their effects potentiate one another. Benzodiazepines increase the frequency in which the chlorine ion pore opens on the GABA A receptor while barbiturates increase the duration in which they are open, meaning when both are consumed, the ion pore will open more frequently and stay open longer .
Benzodiazepine overdose is a medical emergency that may lead to a coma, permanent brain injury or death if not treated promptly and properly. Symptoms of a benzodiazepine overdose may include severe thought deceleration , slurred speech , confusion , delusions , respiratory depression , coma or death. Benzodiazepine overdoses may be treated effectively in a hospital environment, with generally favorable outcomes.
Benzodiazepine overdoses are sometimes treated with flumazenil , a GABA A antagonist  , however care is primarily supportive in nature. Although many drugs are safe on their own, they can become dangerous and even life-threatening when combined with other substances. Even if the medication is taken as prescribed, both dependency and addiction may easily develop.
Clonazepam abuse becomes an issue in those taking this drug for a long period of time, in higher than recommended doses, or those that use the medication for reasons other than those prescribed. Clonazepam Effects Quiz question 1. Even those taking clonazepam with a legitimate prescription can experience tolerance, dependency and, eventually, find themselves struggling with an addiction.
The drug works by interacting with GABA receptors in the brain. This inhibitory neurotransmitter serves to slows brain activity. This is helpful since many theorize that anxiety may be caused by an overabundance of brain activity. The common short-term effects of this clonazepam:. Clonazepam Effects Quiz question 2. If you or a loved one is struggling with clonazepam addiction, please call Who Answers? Doing so can provide you with more information about treatment options to lessen the impact of clonazepam in your life.
Clonazepam Effects Quiz question 3. Clonazepam can cause dangerous central nervous system depression , leading to markedly impaired alertness and slowed bodily functions, especially when taken recreationally or in doses higher than recommended. There are a number of side effects of clonazepam, especially if you take it for a long period of time or at high doses.
In addition, clonazepam is reported to increase suicidal ideation, or suicidal thoughts in some people taking the drug. If you feel depressed, restless or suicidal soon after starting clonazepam, you should immediately alert your doctor. Taking a higher dosage than prescribed, more frequently than prescribed, or taking a substance that is prescribed to someone else is an ill-advised, dangerous course of action that can lead to overdose.
Effects of benzodiazepine overdose can include:. Clonazepam Effects Quiz question 4. Clonazepam is not generally recommended for long-term use because it is known to be a habit-forming substance. Over time, the patient's body tends to build tolerance to clonazepam. Users who have developed a tolerance may need to take higher or more frequent doses of clonazepam to get the relaxation and anti-anxiety effects they were getting when they originally began taking it.
Clonazepam Effects Quiz question 5. You don't have to live with clonazepam addiction. Learn about rehab now. As mentioned, in parallel with the phenomenon of tolerance, patients often experience physical dependence to clonazepam. The body begins to essentially require the drug for normal function. Patients who do not continue to take clonazepam may grow violently ill as they experience the onset of a debilitating benzodiazepine withdrawal syndrome.
Shakiness, shortness of breath, nausea and other physical effects may occur along with psychological effects such as mood swings, increased anxiety, agitation, and depression if a person abruptly stops taking clonazepam. Abrupt cessation of benzodiazepines is never recommended, as seizure and convulsion may be the result—placing one's life in peril.
When someone stops taking clonazepam they will experience a rebound effect. This means that the problems that the medication is designed to treat will present with great intensity and duration. If someone is using the medication to manage anxiety, anxious symptoms will reappear with increased worry, agitation, and nervousness. To receive assistance with a sedative abuse disorder or to help someone dependent on clonazepam, call our helpline at Who Answers?
Sudden withdrawal from clonazepam can be potentially life threatening due to the unwanted withdrawal symptoms. Sudden cessation of long-term clonazepam use can lead to marked agitation, neural excitation, and withdrawal seizure activity , so medical supervision is essential for someone looking to cease use of this drug. Usually, patients go to a detox center for a period of time to gradually withdraw from the drug in a safe environment.
Doctors at the detox center may give patients other medications or treatments to help with the uncomfortable physical effects of withdrawal from this drug. Medical supervision may also help manage psychological symptoms such as mood swings, hallucinations, and depression. Rehab is usually focused on the psychological reasons for addiction and planning ways to live a happier life without use of the substance. Patients may receive individual and group therapy sessions as well become active participants in support group sessions, benefiting from the camaraderie and encouragement of others working through similar recovery issues.
Patients live at the rehab facility with other people who are learning how to live without addictive substances. Rehab may last anywhere from 30 days to one year, depending on a number of factors including severity of the addiction, progress in treatment, and outside supports. Outpatient programs allow the patient to return home and resume his or her normal activities while continuing to get treatment that could be daily, weekly, or less frequently based on their stage in recovery.
Outpatient programs are also options for those who are unable to attend an inpatient facility due to cost or other obligations. Rather than moving to an outpatient setting after rehab, some patients may choose to live in a sober living facility or halfway house upon completing treatment. These homes give patients some freedom.