Clonazepam overdose uptodate medical evidence

By | 05.02.2018

clonazepam overdose uptodate medical evidence

American Society of Health-System Pharmacists. Share Email Print Feedback Close. None declared for Dr. Pharmacokinetics and drug interactions update for new antipsychotics. Treatment of benzodiazepine overdose with flumazenil. Benzodiazepine toxicity

Overdosing on Klonopin is rarely lethal. If the person overdoses on Klonopin alone, they will likely experience the effects outlined above and require medical treatment and monitoring. Most deaths from overdose on Klonopin and other benzodiazepines are the result of taking the medication with alcohol or other drugs that depress the central nervous system.

This combination can lead to fatal suppression of breathing. A person who overdoses on Klonopin should talk to his or her physician about whether to continue taking the medication. In addition, many people who abuse Klonopin may be abusing other drugs and should seek help from a substance abuse program. Outpatient rehab programs allow you to live at home while receiving treatment at a rehab facility. Most programs consist of individual and group therapy, but some may include medical supervision and detox.

Inpatient or residential programs help people uncover the reasons behind their addiction and avoid relapse. People recovering from Klonopin abuse or dependence may participate in individual and group therapy sessions, step meetings, art or music therapy, addiction education sessions, and recreational activities. These are self-help programs in which people with similar addictions support each other in recovery.

Twelve-step programs offer a more spiritual approach, while nonstep programs are more secular and evidence-based. Treatment may include addiction recovery therapies that can also help people learn how to manage their anxiety without medication. Cognitive behavioral therapy Also known as CBT, this therapy helps users recognize the thoughts that lead to drug abuse and teaches relapse prevention skills.

CBT can also be used to help people overcome panic attacks. Individual counseling is One-on-one therapy with a licensed counselor can help the user work through issues surrounding addiction , such as mental health conditions or trauma. A therapist can also help a person learn how to live sober and help the person practice relapse prevention techniques. Group therapy brings together people who are struggling with addiction.

Users realize they are not the only ones who have problems with drug abuse, and they can receive support and give feedback to others in recovery. Call us at Who Answers? Get the help you need to prevent another overdose or prevent the consequences of Klonopin abuse. National Alliance on Mental Illness. Help for Klonopin Addiction. The American Psychiatric Association and the National Institute of Clinical Excellence have treatment and diagnostic guidelines available for cases of substance abuse and self-harm.

Prehospital care for patients who have overdosed on benzodiazepines BZDs includes the following:. Naloxone can be administered at a very low dose 0. An important caveat is that although the administration of 0. This can result in aspiration of gastric contents in patients who are unable to protect their airway because of sedation from the BZD. Its use in acute BZD is controversial, however, and its risks usually outweigh any benefit.

Flumazenil does not consistently reverse central respiratory depression due to BZDs, and over half the patients in a large multicenter study experienced re-sedation after use. In long-term BZD users, flumazenil may precipitate withdrawal and seizures; in patients taking BZDs for a medical condition, flumenazil may result in exacerbation of the condition. In addition to those patients on long-term BZD use, flumazenil should not be used in any patient at an increased risk of having a seizure, including those with a seizure history, head injury, co-ingestion of BZD and tricyclic antidepressant or other proconvulsant, or even a possible ingestion of a proconvulsant.

Antidotes for toxicological emergencies: Am J Health Syst Pharm. Drug Abuse Warning Network, April 4, ; Accessed: Characteristics of alprazolam-related deaths compiled by a centralized state medical examiner. Circumstances and toxicology of sudden or unnatural deaths involving alprazolam. Alprazolam is relatively more toxic than other benzodiazepines in overdose. Br J Clin Pharmacol. Treatment of patients with substance use disorders, second edition.

Basic Clin Pharmacol Toxicol. Treatment of benzodiazepine overdose with flumazenil. J Toxicol Clin Toxicol. Michael J Burns, MD is a member of the following medical societies: David C Lee, MD is a member of the following medical societies:


1 thoughts on “Clonazepam overdose uptodate medical evidence

  1. Gardajas

    Klonopin helps my anxiety, panic disorder, and insomnia... I take it on an as needed basis and it's one mg tablet

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